The Placer Mosquito and Vector Control District is governed by a seven-member Board of Trustees. One trustee is appointed by each incorporated city or town and the Placer County Board of Supervisors appoints one. To be appointed, the member must be a resident voter of the representative city (or county for county member) in the District. Board member duties and responsibilities include setting policy, establishing the budget, approving expenditures, and retaining legal council. The trustees serve a two- or four-year term without compensation, but do receive an in lieu travel expense of $100 for attending each regularly scheduled board meeting.

The regularly scheduled board meetings are held on the second Thursday of each month, starting at 4:30 p.m., at the District office at 150 Waverly Drive, Lincoln, CA 95648. All meetings are open to the public.